Main Cast
• Rajeev Parameshwar as Balakrishnan (a.k.a. "Balan") Balan is the eldest son of Lakshmi and Krishnan, and the elder brother of Hari, Shivan, Kannan. He is the current head of the Santhwanam Family and the main operator of Krishna Stores. He is Devi's husband, and always expresses his regret that Devi doesn't bear children because of him. He also leads the financial matters of the Krishna Stores. He is a Pre-Degree Graduate
• Chippy Renjith as Sreedevi Balakrishnan (a.k.a. "Devi") Devi is Sethu's sister and Balan's wife. She is Hari, Shiva, and Kannan's sister-in-law, which makes her Lakshmi's eldest daughter-in-law. She is characterized as a sweet, talented. Viewers see her as a very lovable and sacrificial person who takes care of her in-laws. She sometimes helps Balan out at Krishna Stores. She is a B.Com graduate with First Class.
• Girish Nambiar as Harikrishnan (a.k.a. "Hari") Hari is the second oldest son of Lakshmi and Krishnan, and Appu's husband. He is an MBA Graduate. He is shown to support the Santhwanam family more than his wife Aparna in all circumstances.
• Raksha Raj as Aparna Harikrishnan (a.k.a. "Appu") Appu is Hari's wife and Thampi's daughter. She is also a Master's degree holder. She is shown to love her father and her husband more than her life. After some difficulty, she adjusted to the lifestyle of the Santhwanam family.
• Sajin TP as Shivaramakrishnan (a.k.a. "Shivan") Shivan is the third son of Lakshmi and Krishnan, as well as Anju's husband. He is a meritorious student. Due to their family's circumstances, he only studied until matriculation. He always has a local dressing style and does not like to wear formal clothes. Like his mother, he hates Savitri and Jayanthi. He is shown to have a better memory than his other brothers. He loves Anjali but is struggling to express his feelings. He is the least educated of the 4 Santhwanam Brothers.
• Dr. Gopika Anil as Anjali Shivaramakrishnan (a.k.a. "Anju") Anju is the daughter of Shankaran and Savitri, as well as Shivan's wife. She loves Shiva but struggles to express it. She is a B.Com graduate. She has always dreamt of becoming a member of Santhwanam Family.
• Achu Sugandh as Muralikrishnan (a.k.a. "Kannan") Kannan is the youngest son of Lakshmi and Krishnan. He is a college student. He is talkative, childish and naughty.This made him as the cutest member of the family. His most favorite brother is Shivan.
• Girija Preman as Lakshmi Lakshmi is Shankaran's sister. She is also Krishnan's widow and is the mother of Balan, Hari, Shivan, and Kannan. She is the mother-in-law of Devi, Appu, and Anjali. She is also Anjali's aunt. She hates Savitri, her sister-in-law, and Jayanthi, Savitri's niece. She hated Devi for a few days after her marriage to Balan; she also briefly hated Appu for causing a scene in the marriage hall. She is a paralyzed woman.

• • Yathikumar as Shankaran Anju's father, Lakshmi's brother, and Savithri's husband. He was once a rich man but lost his assets due to his honest behaviour.
• Divya Binu as Malikapurackal Savithri Shankaran Anju's mother, Shiva's mother-in-law, Shankaran's wife, and Jayanthi's maternal aunt. She hates Devi and always picks fights with her husband. She also hates the Santhwanam family. She always supports the Malikapurackal Brothers.
• Apsara as Jayanthi Sethu Sethu's wife, Devi's sister-in-law, Subhadra's daughter-in-law, Savithri's niece, Indira, and Savithri's brother's daughter. She hates Devi.
• Kailas Nath as Narayana Pillai (a.k.a Pilla) Friend of Krishnan and staff of Krishna Stores. He hails from Nagercoil. The Krishna brothers consider him a fatherlike figure and a member of the Santhwanam family.
• Bijesh Avanoor as Sethu Devi's brother, Jayanthi's husband, Balan's close friend, and Subhadra's son. He owns an event management company.
• Geetha Nair as Subhadra Sethu and Devi's mother; Jayanthi and Balan's mother-in-law. She is Lakshmi's closest friend.
• Rohit as Rajasekharan Thampi Appu's father. He is a Rich Landlord, who lives at his mansion residence "Amaravathy." He owns a lot of land and is only obedient to his sister, Rajeshwari.
• Zeenath as Rajeshwari Rajasekharan Thampi's elder sister, Appu's aunt, and Somasekharan MLA's wife. She lives in Wayanad and comes to visit Thampi sometimes.
• Dr. Nita Gosh as Ambika Thampi Thampi's wife, mother of Appu and Ammu, mother-in-law of Hari.
• Kalyani as Amritha Thampi (a.k.a "Ammu") Thampi's younger daughter and Appu's sister. She is a B.Tech college student.
• Sreelakshmi Sreekumar as Jancy Anju's best friend and former classmate who works in Chennai.
• Liju Mathew Abraham as Deepu
• Hari's best friend

• • M Renjith in a promo episode
• J. Pallassery in a promo episode
• Aadithyan in a promo episode
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